Breast Cancer Treatment and Cardiovascular Considerations

Maryam Mehrpooya (1), Jeyran Zebardast (2), Mahdi Aghili (3)
(1) Cardiology Department, Tehran University of Medical Sciences, Tehran, Iran, Iran, Islamic Republic of,
(2) MS, E-learning in Medical Education, Tehran University of Medical Sciences, Tehran, Iran, Iran, Islamic Republic of,
(3) Department of Radiation Oncology, Radiation Oncology Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran, Iran, Islamic Republic of


Background: Breast cancer is the most frequently occurring cause of cancer-related mortality in women all around the world. However, the risk of cardiovascular diseases increases in parallel with dramatic improvements in target-specific treatment for breast cancer. The aim of this review was to show the importance of cardiovascular involvement in patients with breast cancer.
Methods: Published literature, regarding breast cancer and cardiovascular involvements, as well as cardiovascular complications of current treatments for breast cancer, including chemotherapy and radiotherapy, was reviewed.
Results: Review of our data revealed that there are extensive direct and indirect impacts of breast cancer on the cardiovascular system. Cardiovascular complications of breast cancer are common and range from cardiomyopathy, pericardial involvement, venous thromboembolism, and arterial thrombosis to some uncommon problems.
Conclusion: Early detection of cardiovascular damages from breast cancer is strongly recommended. Considering the significant cardiovascular complications of both breast cancer and its treatment, early recognition, prevention, and management of these complications, even the minor ones, improve prognosis and survival of patients with breast cancer.

Full text article

Generated from XML file


Maryam Mehrpooya (Primary Contact)
Jeyran Zebardast
Mahdi Aghili
Mehrpooya M, Zebardast J, Aghili M. Breast Cancer Treatment and Cardiovascular Considerations. Arch Breast Cancer [Internet]. 2018 Mar. 29 [cited 2024 Jul. 14];5(1):3-10. Available from:

Article Details

Most read articles by the same author(s)

Similar Articles

You may also start an advanced similarity search for this article.