FDG PET Application for Management of Breast Cancer Patient: A Narrative Review

Saeed Farzanehfar (1), Farahnaz Aghahoseini (2), Marzieh Peyman (3), Mehrshad Abbasi (4)
(1) , Iran, Islamic Republic of,
(2) , Iran, Islamic Republic of,
(3) , Iran, Islamic Republic of,
(4) a:1:{s:5:"en_US";s:103:"Department of Nuclear Medicine, Vali-asr Hospital, Tehran University of Medical Sciences, Tehran, Iran.";}, Iran, Islamic Republic of

Abstract

Background: The application of FDG PET/CT scan for assessment of patients with breast cancer is increasing. The cost effectiveness of the application could be different in a developing country with limited PET scanners and treatment priorities
Methods: Open discussions of the PET reviewers from 2 out of 4 PET centers of Tehran, the capital city of Iran, were organized to provide insight into their opinions on the indications of FDG PET in breast cancer patients.


Results: The sensitivity of FDG PET scan is high for detection of distant metastases; however, assessment of lymph node pathology and the local extension of the breast cancer are questionable. Considering the cost of the procedure itself and the downstream diagnostic procedures, its application and diagnostic accuracy are hindered for breast cancer screening, staging, and assessment of response to treatment and prognosis. The advantages and disadvantages of FDG PET CT and dedicated breast FDG PET scan have been briefed in different clinical scenarios with a focus on limitations faced by a developing country.
Conclusion: We suggest reserving the use of FDG PET for selected cases of suspected but not proven recurrent disease and in patients with high risk of metastasis before high risk surgery.

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Authors

Saeed Farzanehfar
Farahnaz Aghahoseini
Marzieh Peyman
Mehrshad Abbasi
meabbasi@tums.ac.ir (Primary Contact)
1.
Farzanehfar S, Aghahoseini F, Peyman M, Mehrshad Abbasi. FDG PET Application for Management of Breast Cancer Patient: A Narrative Review. Arch Breast Cancer [Internet]. 2020 May 31 [cited 2024 Apr. 18];:54-8. Available from: https://www.archbreastcancer.com/index.php/abc/article/view/297

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