Synchronous Invasive Lobular Carcinoma of Breast With Hodgkin Lymphoma: A Case Report

Massoome Najafi, Afsaneh Alikhassi, Sanaz Zand, Shahram Movafaghi, Gholamreza Toogeh


Background: Multiple Primary Malignant Neoplasms (MPMN) is a well-known entity. Most of these tumors are metachronous. The treatment of Hodgkin lymphoma increases the risk of developing second malignancies including breast cancer. However, the synchronous occurrence of breast cancer and Hodgkin lymphoma is rare.

Case presentation: We presented a case of a 31-year-old woman with simultaneous diagnosis of lobular carcinoma of the breast and Hodgkin lymphoma. The patient underwent modified radical mastectomy followed by hormone therapy as adjuvant treatment of breast cancer and simultaneous chemotherapy for Hodgkin lymphoma.

Conclusion: To the best of our knowledge, this is the first report of coexistence of breast cancer and Hodgkin lymphoma. Synchronous cancers present therapeutic challenges to the clinicians, and the treatment planning should be discussed in a multidisciplinary team.


Breast cancer; Synchronous tumor; Hodgkin lymphoma

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                                     Archives of Breast Cancer, eISSN: 2383-0433, pISSN: 2383-0425